The project is to study the mechanisms of neuronal dysfunction caused by pathological phosphorylation (with emphasis on the recently discovered polo-like kinases) and aggregation of the Parkinson's disease protein α-synuclein and explore immune therapeutic approaches. Transgenic mice and cell cultures are the primary model systems for this project. Methods include behavioral assays, experimental neuropathology, and a wide range of molecular, cellular and biochemical methods, as well as advanced imaging techniques.
They are looking for a highly motivated, team-oriented enthusiastic individual with a strong background in neuroscience animal research and molecular cell biology. Successful applicants will be enrolled in an Initial Training Network of the European Union 7th Framework Program and the Graduate Training Center of Neuroscience, University of Tübingen. Non-German residents, preferentially European citizens are eligible.
Interested individuals with a diploma/masters degree in life sciences (e.g. neuroscience, biology) are invited to send applications to:
Prof. Dr. Philipp Kahle
Laboratory of Functional Neurogenetics
Hertie Institute for Clinical Brain Research
Otfried Müller Str. 27
72076 Tübingen, Germany
E-Mail: philipp.kahle@uni-tuebingen.de
http://www.hih-tuebingen.de/nd/research/funct-neurogenet/
www.neuroschool-tuebingen.de
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